The Nurse's office, or the Infirmary, is a minor location in The Amazing World of Gumball, located in Elmore Junior High. It is where Joan Markham, the school nurse, works. Teri spends most of her time in this office.
- "The Mystery": Miss Simian takes Principal Brown to the nurse's office after the students find him in Gumball's locker.
- "The Sock": Gumball and Darwin are there because Darwin's head exploded and needed to be plastered back together.
- "The Banana": Banana Joe ends up there after pulling parts of his face off.
- "The Bet": Gumball has Bobert insult Ms. Markham and make out with the defibrillator here.
- "The Virus": Gumball, Darwin, and Teri are in there with Ms. Markham.
- "The Sidekick": It appears in the montage of Tobias' many excuses for returning the game late.
- "The Coach": It is seen when Gumball is trying to get Ms. Markham to give him a note to skip his gym class.
- "The Joy": Miss Simian takes an infected Gumball and Darwin to the office.
- "The Allergy": Gumball takes Darwin to the nurse's office to help him with his allergy.
- "The Society": Principal Brown is in there because he got painfully hurt by Gumball.
- "The Advice": Many students end up there due to Gumball and Darwin's antics.
- "The Parasite": Ms. Markham examines Anais and Jodie's fused bodies here.
- "The Stories": Principal Brown and Ms. Markham discuss their made-up affair in the office as part of the plan to give Molly a story worth telling.
- "The Matchmaker": Darwin is taped to a wall in the office while Gumball tries to lure Teri there.